Pineapple Express is a sativa dominant marijuana strain made by crossing Trainwreck with Hawaiian. While this strain rose to fame on the silver screen in 2008 amidst the release of Pineapple Express, it is a real strain that you can find on the shelves of dispensaries across the country. Since then, this strain has become a favorite in the hearts and minds of cannabis lovers. Pineapple Express produces long-lasting energetic effects that you can feel right away. Pineapple Express’s high THC may make you feel buzzy, alert, and creative. The best time to smoke Pineapple Express is in the morning, afternoon, or early evening hours.  Pineapple Express is chosen to treat a lot of medical problems including anxiety and stress. However, it is even more effective at curing the symptoms of chronic depression at the same time. After a smoke, you will realize Pineapple Express is calming and stimulating at the same time. Not only will it heighten all your senses but you will feel energized all the while observing an increase in focus, awareness and creativity.